DodecaGreen The Green Chemistry Portal

DodecaGreen Score.

Assess a chemical process against all twelve Principles of Green Chemistry using an anchored rubric. Score each principle 0–5 and watch the radar chart and overall score update live. All data stays in your browser — nothing is sent to any server.

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What is the DodecaGreen Score — and how does it work?

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The DodecaGreen Score is a holistic, rubric-based assessment of how well a chemical process adheres to the 12 Principles of Green Chemistry (Anastas & Warner, 1998). Unlike single metrics such as atom economy or E-factor, it provides a 360° view across all principles simultaneously.

GoalIdentify the strengths and weaknesses of a process across all 12 Principles and guide targeted improvements.
HowAssign each principle a score of 0–5 using the anchored rubric. The radar chart visualises balance; the Score summarises overall performance.
OutputA percentage score (0–100%), an interactive radar plot, and a per-principle breakdown with comments, interpretation, and export options.

The formula

$$\text{DodecaGreen Score (\%)} = \frac{\displaystyle\sum_{i=1}^{12} P_i}{60} \times 100$$
SymbolTerm
$P_i$Score for Principle $i$ (0 = very poor / no data, 5 = excellent); maximum 5 per principle
60Maximum possible total (12 principles × 5)

Score interpretation

DodecaGreen ScoreRatingTypical interpretation
≥ 75%ExcellentProcess exemplifies green chemistry across most principles
50–74%GoodStrong in several areas; targeted improvements possible
35–49%ModerateNotable gaps; multiple principles need attention
< 35%Needs improvementFundamental redesign recommended across several principles

Strengths and limitations

✓ Strengths

  • Holistic — covers all 12 Principles simultaneously
  • Flexible — works at any stage from lab-scale to industrial
  • Communicable — percentage is easy to understand and compare
  • Reveals imbalances that single metrics miss
  • Anchored rubric criteria improve inter-rater reliability

⚠ Limitations

  • Subjective element — expert judgement and available data required
  • All 12 Principles weighted equally (context may differ)
  • A high overall score can mask a very poor score on one critical principle
  • Does not replace quantitative metrics — use alongside E-factor, AE, PMI
  • Inter-rater reliability improves with the anchored rubric, but is not guaranteed

The DodecaGreen Score in context: complementary metrics

MetricWhat it measuresStage
DodecaGreen ScoreHolistic rubric assessment across all 12 PrinciplesAny
Atom Economy (AE)Fraction of reactant mass in desired product (theoretical)Design
E-factorTotal waste per unit of product (includes solvents)Experimental
PMITotal input mass per unit productExperimental
RMECombined practical efficiency (AE × yield × stoichiometry)Experimental
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Assessment rubric

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Each level is anchored to measurable criteria to improve inter-rater reliability. Use this table alongside the individual principle guides (click any principle name in the Score section below).

Principle 0 — Very Poor or Missing Data 1 — Poor 2 — Needs improvement 3 — Satisfactory 4 — Good 5 — Excellent
1. PreventionEf ≥ 4.002.00 ≤ Ef < 4.001.00 ≤ Ef < 2.000.50 ≤ Ef < 1.000.25 ≤ Ef < 0.50Ef < 0.25
2. Atom EconomyAE < 30%30 ≤ AE < 45%45 ≤ AE < 60%60 ≤ AE < 75%75 ≤ AE < 90%AE ≥ 90%
3. Less Hazardous Synthesis>1 GHS Cat. 1–2Only 1 GHS Cat. 1–2≥1 GHS Cat. 3≥1 GHS Cat. 4Only GHS Cat. 5No GHS hazard codes
4. Designing Safer ChemicalsNo LD50/LC50 dataLD50 < 5 mg/kg or LC50 < 0.5 mg/L5 ≤ LD50 < 5050 ≤ LD50 < 300300 ≤ LD50 < 2000LD50 ≥ 2000 mg/kg
5. Safer SolventsMultiple GSK "red" solventsSingle GSK "red" solventMultiple GSK "yellow"Only one GSK "yellow"Only GSK "green" solventsNo solvents used
6. Energy EfficiencykWh ≥ 205 ≤ kWh < 202 ≤ kWh < 50.5 ≤ kWh < 20.05 ≤ kWh < 0.5kWh < 0.05
7. Renewable Feedstocks0% renewable0–20% renewable20–40% renewable40–60% renewable60–80% renewable80–100% renewable
8. Reduce Derivatives≥5 deriv. steps4 steps3 steps2 steps1 step0 steps
9. CatalysisNo catalystTON = 1 (stoichiometric)1 < TON ≤ 5050 < TON ≤ 10001000 < TON ≤ 100 000TON > 100 000
10. Design for Degradationt½ ≥ 365 d or no data180 ≤ t½ < 365 d60 ≤ t½ < 180 d10 ≤ t½ < 60 d1 ≤ t½ < 10 dt½ < 1 d
11. Real-time AnalysisNo analysisPost-reaction onlyOccasional in-processFrequent in-processContinuous in-processAutomated monitoring & feedback
12. Inherently Safer ChemistryΔT > 200 K or ΔP > 50 bar or explosive100 < ΔT ≤ 200 K or 10 < ΔP ≤ 50 bar50 < ΔT ≤ 100 K or 1 < ΔP ≤ 10 bar0 < ΔT ≤ 50 K and 1 < ΔP ≤ 10 bar, Cat. 4–5ΔT ≤ 50 K and ΔP = 0, Cat. 4–5ΔT = 0, ΔP = 0, no GHS codes

AE = atom economy · Ef = E-factor · GHS = Globally Harmonized System · TON = turnover number · t½ = environmental half-life

Score your process

Use the rubric above to assign each principle a score of 0–5. Click a principle name to open its full guide page.

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Check the scoring rubric first
Use the anchored rubric in to assign each principle a consistent 0–5 score before moving the sliders.

Results

Average Score
/5
At Maximum (5/5)
of 12
At Minimum (0/5)
of 12
DodecaGreen Score
0%25%50%75%100%
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Detailed breakdown & interpretation

Principle Score Level Comment

Interpretation & recommendations

Adjust the sliders above to see the interpretation.

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Experiment details

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Export

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Export the current assessment as a PDF report, CSV data file, or SVG radar chart.

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Save & load sessions

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Data is stored only in your browser's localStorage — nothing is sent to any server. Delete all data at any time using the button below.

No saved sessions yet.
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Where can I read more?

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  1. P. T. Anastas and J. C. Warner, Green Chemistry: Theory and Practice, Oxford University Press, 1998. — Original statement of the 12 Principles of Green Chemistry.
  2. R. A. Sheldon, "The E-Factor 25 years on: the rise of green chemistry and sustainability," Green Chem., 2017, 19, 18–43. DOI
  3. C. Jiménez-González et al., "Using the Right Green Yardstick," Org. Process Res. Dev., 2011, 15, 912–917. DOI
  4. B. M. Trost, "Atom Economy: a Challenge for Organic Synthesis," Angew. Chem. Int. Ed., 1995, 34, 259–281.
  5. ACS Green Chemistry Institute Pharmaceutical Roundtable, PMI/E-factor benchmarking reports (ongoing).
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Contributors

Roles follow the CRediT taxonomy (Contributor Roles Taxonomy), adapted for educational software. Hover a contributor's name for a summary, or a column header for the definition of that role.

Contributor

© 2024– DodecaGreen Project. All rights reserved. · Last updated: 03/06/2026

This portal was built with the assistance of a large language model (Claude, Anthropic), which was used to generate and refine code, articulate and structure contributed ideas within the defined page format, and support iterative design decisions. All scientific content, conceptual frameworks, pedagogical choices, and final outputs were directed, reviewed, and verified by the contributors listed above.

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How do I cite this page?

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If you use this tool in teaching or published work, please cite the DodecaGreen portal as the source.

Reference
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